Prof. Michaela Wimmerová, Ph.D.

2017

• HOUSER, J; KOZMON, S; MISHRA, D; MISHRA, SK; ROMANO, PR; WIMMEROVA, M; KOCA, J, 2017:Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL. PLOS ONE 12 (12)
• JANCARIKOVA, G; HOUSER, J; DOBES, P; DEMO, G; HYRSL, P; WIMMEROVA, M, 2017:Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLOS PATHOGENS 13 (8)

2016

• FUJDIAROVA, E; GAJDOS, L; WIMMEROVA, M, 2016:Study of lectins from Photorhabdus luminescens to reveal their function in P. luminescens life cycle. FEBS JOURNAL 283 , p. 152 - 152.
• KERR, SC; FISCHER, GJ; SINHA, M; MCCABE, O; PALMER, JM; CHOERA, T; LIM, FY; WIMMEROVA, M; CARRINGTON, SD; YUAN, SP; LOWELL, CA; OSCARSON, S; KELLER, NP; FAHY, JV, 2016:FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. PLOS PATHOGENS 12 (4)
• KUMAR, A; SYKOROVA, P; DEMO, G; DOBES, P; HYRSL, P; WIMMEROVA, M, 2016:A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure. JOURNAL OF BIOLOGICAL CHEMISTRY 291 (48), p. 25032 - 25049.
• NORTON, P; COMUNALE, MA; HERRERA, H; WANG, MJ; HOUSER, J; WIMMEROVA, M; ROMANO, PR; MEHTA, A, 2016:Development and application of a novel recombinant Aleuria aurantia lectin with enhanced core fucose binding for identification of glycoprotein biomarkers of hepatocellular carcinoma. PROTEOMICS 16 (24), p. 3126 - 3136.

2015

• HOUSER, J; KOMAREK, J; CIOCI, G; VARROT, A; IMBERTY, A; WIMMEROVA, M, 2015:Structural insights into Aspergillus fumigatus lectin specificity: AFL binding sites are functionally non-equivalent. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 71 , p. 442 - 453.
• SEHNAL, D; VAREKOVA, RS; PRAVDA, L; IONESCU, CM; GEIDL, S; HORSKY, V; JAISWAL, D; WIMMEROVA, M; KOCA, J, 2015:ValidatorDB: database of up-to-date validation results for ligands and non-standard residues from the Protein Data Bank. NUCLEIC ACIDS RESEARCH 43 (D1), p. D369 - D375.

2014

• ADAMOVA, L; MALINOVSKA, L; WIMMEROVA, M, 2014:New Sensitive Detection Method for Lectin Hemagglutination using Microscopy. MICROSCOPY RESEARCH AND TECHNIQUE 77 (10), p. 841 - 849.
• DEMO, G; PAPOUSKOVA, V; KOMAREK, J; KADERAVEK, P; OTRUSINOVA, O; SRB, P; RABATINOVA, A; KRASNY, L; ZIDEK, L; SKLENAR, V; WIMMEROVA, M, 2014:X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. JOURNAL OF STRUCTURAL BIOLOGY 187 (2), p. 174 - 186.
• KRIZ, Z; ADAM, J; MRAZKOVA, J; ZOTOS, P; CHATZIPAVLOU, T; WIMMEROVA, M; KOCA, J, 2014:Engineering the Pseudomonas aeruginosa II lectin: designing mutants with changed affinity and specificity. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 28 (9), p. 951 - 960.
• VAREKOVA, RS; JAISWAL, D; SEHNAL, D; IONESCU, CM; GEIDL, S; PRAVDA, L; HORSKY, V; WIMMEROVA, M; KOCA, J, 2014:MotiveValidator: interactive web-based validation of ligand and residue structure in biomolecular complexes. NUCLEIC ACIDS RESEARCH 42 (W1), p. W227 - W233.

2013

• DEMO, G; FLIEDROVA, B; WEIGNEROVA, L; WIMMEROVA, M, 2013:Crystallization and preliminary X-ray crystallographic analysis of recombinant -mannosidase from Aspergillus niger. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 69 , p. 288 - 291.
• HOUSER, J; KOMAREK, J; KOSTLANOVA, N; CIOCI, G; VARROT, A; KERR, SC; LAHMANN, M; BALLOY, V; FAHY, JV; CHIGNARD, M; IMBERTY, A; WIMMEROVA, M, 2013:A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity. PLOS ONE 8 (12)
• TVAROSKA, I; KOZMON, S; WIMMEROVA, M; KOCA, J, 2013:A QM/MM Investigation of the Catalytic Mechanism of Metal-Ion-Independent Core 2 beta 1,6-N-Acetylglucosaminyltransferase. CHEMISTRY-A EUROPEAN JOURNAL 19 (25), p. 8153 - 8162.

2012

• AUDFRAY, A; CLAUDINON, J; ABOUNIT, S; RUVOEN-CLOUET, N; LARSON, G; SMITH, DF; WIMMEROVA, M; LE PENDU, J; ROMER, W; VARROT, A; IMBERTY, A, 2012:Fucose-binding Lectin from Opportunistic Pathogen Burkholderia ambifaria Binds to Both Plant and Human Oligosaccharidic Epitopes. JOURNAL OF BIOLOGICAL CHEMISTRY 287 (6), p. 4335 - 4347.
• CECIONI, S; PRALY, JP; MATTHEWS, SE; WIMMEROVA, M; IMBERTY, A; VIDAL, S, 2012:Rational Design and Synthesis of Optimized Glycoclusters for Multivalent Lectin-Carbohydrate Interactions: Influence of the Linker Arm. CHEMISTRY-A EUROPEAN JOURNAL 18 (20), p. 6250 - 6263.
• FROMMEL, J; SOURAL, M; TYLICHOVA, M; KOPECNY, D; DEMO, G; WIMMEROVA, M; SEBELA, M, 2012:Plant aminoaldehyde dehydrogenases oxidize a wide range of nitrogenous heterocyclic aldehydes. AMINO ACIDS 43 (3), p. 1189 - 1202.
• HOUSER, J.;J. KOMAREK;N. KOSTLANOVA;G. CIOCI;A. IMBERTY;M. WIMMEROVA., 2012:Protein oligomerization in Aleuria aurantia lectin family - importance and difficulties. Materials Structure in Chemistry 19 , p. 20 - 21.
• MARCHETTI, R; MALINOVSKA, L; LAMEIGNERE, E; ADAMOVA, L; DE CASTRO, C; CIOCI, G; STANETTY, C; KOSMA, P; MOLINARO, A; WIMMEROVA, M; IMBERTY, A; SILIPO, A, 2012:Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide. GLYCOBIOLOGY 22 (10), p. 1387 - 1398.
• MISHRA, S; ADAMOVA, L; ADAM, J; WIMMEROVA, M; KOCA, J, 2012:Comparison of Docking Software to Predict Saccharide Binding to Proteins Combination with In silico Protein Engineering. GLYCOBIOLOGY 22 (11), p. 1648 - 1649.
• MISHRA, SK; ADAM, J; WIMMEROVA, M; KOCA, J, 2012:In Silico Mutagenesis and Docking Study of Ralstonia solanacearum RSL Lectin: Performance of Docking Software To Predict Saccharide Binding. JOURNAL OF CHEMICAL INFORMATION AND MODELING 52 (5), p. 1250 - 1261.
• SEHNAL, D; VAREKOVA, RS; HUBER, HJ; GEIDL, S; IONESCU, CM; WIMMEROVA, M; KOCA, J, 2012:SiteBinder: An Improved Approach for Comparing Multiple Protein Structural Motifs. JOURNAL OF CHEMICAL INFORMATION AND MODELING 52 (2), p. 343 - 359.
• TVAROSKA, I; KOZMON, S; WIMMEROVA, M; KOCA, J, 2012:Substrate-Assisted Catalytic Mechanism of O-GIcNAc Transferase Discovered by Quantum Mechanics/Molecular Mechanics Investigation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 134 (37), p. 15563 - 15571.
• VISACKA, K; HOFR, C; WILLCOX, S; NECASOVA, I; PAVLOUSKOVA, J; SEPSIOVA, R; WIMMEROVA, M; SIMONICOVA, L; NOSEK, J; FAJKUS, J; GRIFFITH, JD; TOMASKA, L, 2012:Synergism of the Two Myb Domains of Tay1 Protein Results in High Affinity Binding to Telomeres. JOURNAL OF BIOLOGICAL CHEMISTRY 287 (38), p. 32206 - 32215.
• WIMMEROVA, M; KOZMON, S; NECASOVA, I; MISHRA, SK; KOMAREK, J; KOCA, J, 2012:Stacking Interactions between Carbohydrate and Protein Quantified by Combination of Theoretical and Experimental Methods. PLOS ONE 7 (10)

2011

• CECIONI, S; FAURE, S; DARBOST, U; BONNAMOUR, I; PARROT-LOPEZ, H; ROY, O; TAILLEFUMIER, C; WIMMEROVA, M; PRALY, JP; IMBERTY, A; VIDAL, S, 2011:Selectivity among Two Lectins: Probing the Effect of Topology, Multivalency and Flexibility of "Clicked" Multivalent Glycoclusters. CHEMISTRY-A EUROPEAN JOURNAL 17 (7), p. 2146 - 2159.
• GILBOA-GARBER, N; ZINGER-YOSOVICH, KD; SUDAKEVITZ, D; LERRER, B; IMBERTY, A; WIMMEROVA, M; WU, AM; GARBER, NC, 2011:The Five Bacterial Lectins: PA-II, PA-III, RSL, RS-III and CV-III Interactions with Diverse Animal Cells and Glycoproteins. Advances in Experimental Medicine and Biology 705 , p. 155 - 211.
• HAVEL, V; SVEC, J; WIMMEROVA, M; DUSEK, M; POJAROVA, M; SINDELAR, V, 2011:Bambus[n]urils: a New Family of Macrocyclic Anion Receptors. ORGANIC LETTERS 13 (15), p. 4000 - 4003.
• REVESZ, A; SCHRODER, D; SVEC, J; WIMMEROVA, M; SINDELAR, V, 2011:Anion Binding by Bambus[6]uril Probed in the Gas Phase and in Solution. JOURNAL OF PHYSICAL CHEMISTRY A 115 (41), p. 11378 - 11386.
• SULAK, O; CIOCI, G; LAMEIGNERE, E; BALLOY, V; ROUND, A; GUTSCHE, I; MALINOVSKA, L; CHIGNARD, M; KOSMA, P; AUBERT, DF; MAROLDA, CL; VALVANO, MA; WIMMEROVA, M; IMBERTY, A, 2011:Burkholderia cenocepacia BC2L-C Is a Super Lectin with Dual Specificity and Proinflammatory Activity. PLOS PATHOGENS 7 (9)

2010

• KLUMPLER, T; SEDLACEK, V; MAREK, J; WIMMEROVA, M; KUCERA, I, 2010:Crystallization and initial X-ray diffraction studies of the flavoenzyme NAD(P)H:(acceptor) oxidoreductase (FerB) from the soil bacterium Paracoccus denitrificans. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 66 , p. 431 - 434.
• LAMEIGNERE, E; SHIAO, TC; ROY, R; WIMMEROVA, M; DUBREUIL, F; VARROT, A; IMBERTY, A, 2010:Structural basis of the affinity for oligomannosides and analogs displayed by BC2L-A, a Burkholderia cenocepacia soluble lectin. GLYCOBIOLOGY 20 (1), p. 87 - 98.
• MISHRA, NK; KRIZ, Z; WIMMEROVA, M; KOCA, J, 2010:Recognition of selected monosaccharides by Pseudomonas aeruginosa Lectin II analyzed by molecular dynamics and free energy calculations. CARBOHYDRATE RESEARCH 345 (10), p. 1432 - 1441.
• SULAK, O; CIOCI, G; DELIA, M; LAHMANN, M; VARROT, A; IMBERTY, A; WIMMEROVA, M, 2010:A TNF-like Trimeric Lectin Domain from Burkholdeda cenocepacia with Specificity for Fucosylated Human Histo-Blood Group Antigens. STRUCTURE 18 (1), p. 59 - 72.

2009

• HANSEN, SF; BETTLER, E; WIMMEROVA, M; IMBERTY, A; LEROUXEL, O; BRETON, C, 2009:Combination of Several Bioinformatics Approaches for the Identification of New Putative Glycosyltransferases in Arabidopsis. JOURNAL OF PROTEOME RESEARCH 8 (2), p. 743 - 753.
• HOFR, C., SULTESOVA, P., ZIMMERMANN, M., MOZGOVA, I., SCHRUMPFOVA, P. P., WIMMEROVA, M., FAJKUS, J.,, 2009:Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics. BIOCHEMICAL JOURNAL 419 , p. 221 - 228.
• CHEMANI, C; IMBERTY, A; DE BENTZMANN, S; PIERRE, M; WIMMEROVA, M; GUERY, BP; FAURE, K, 2009:Role of LecA and LecB Lectins in Pseudomonas aeruginosa-Induced Lung Injury and Effect of Carbohydrate Ligands. INFECTION AND IMMUNITY 77 (5), p. 2065 - 2075.
• MATEJKOVA, M; ZIDKOVA, J; ZIDEK, L; WIMMEROVA, M; CHMELIK, J; SKLENAR, V, 2009:Investigation of Thermal Denaturation of Barley Nonspecific Lipid Transfer Protein 1 (ns-LTP1b) by Nuclear Magnetic Resonance and Differential Scanning Calorimetry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 57 (18), p. 8444 - 8452.
• TESARIK, R; SEDLACEK, V; PLOCKOVA, J; WIMMEROVA, M; TURANEK, J; KUCERA, I, 2009:Heterologous expression and molecular characterization of the NAD(P)H:acceptor oxidoreductase (FerB) of Paracoccus denitrificans. PROTEIN EXPRESSION AND PURIFICATION 68 (2), p. 233 - 238.
• WIMMEROVA, M; MISHRA, NK; POKORNA, M; KOCA, J, 2009:Importance of oligomerisation on Pseudomonas aeruginosa Lectin-II binding affinity. In silico and in vitro mutagenesis. JOURNAL OF MOLECULAR MODELING 15 (6), p. 673 - 679.

Office 1:	Masarykova univerzita - CEITEC MU Kamenice 753/5, Brno, 625 00, office bud. A5/317
Office 2:	Masarykova univerzita Kamenice 5, Brno, 625 00