Change institution

Structural Biology Seminar Series: NMR of large proteins: Molecular chaperones?

Structural Biology Seminar Series: NMR of large proteins: Molecular chaperones?

You are cordially invited to the lecture "NMR of large proteins: Molecular chaperones?" delivered by Charalampos G. Kalodimos, Rutgers University, USA.

WHEN: Thursday, October 17, 2013, from 14:00
WHERE: Seminar room 1.32, pavilion A11, University campus Bohunice

Abstract:

Molecular chaperones are necessary for maintaining a functional proteome in the cell by preventing the aggregation of unfolded proteins and/or assisting with their folding. Despite the central importance of the binding of chaperones to unfolded substrates, the structural basis of their interaction remains poorly understood. The scarcity of structural data on complexes between chaperones and unfolded client proteins is primarily due to technical challenges originating in the dynamic nature of these complexes.

I will discuss how NMR spectroscopy can be used as an extremely powerful tool to determine the structural and dynamic basis for the recognition and interaction of unfolded proteins by molecular chaperones.

Poster to download can be found HERE.

More CEITEC News ...
Dr. Ondrej Hovorka: Models of magnetic nanoparticles for biomedical applications

29. ledna 2018 9:46

Dr. Ondrej Hovorka: Models of magnetic nanoparticles for biomedical…

LECTURE: Dr. Ondrej Hovorka: Models of magnetic nanoparticles for biomedical applications

Advanced Materials and Nanotechnology Seminar Series 2018: Dr Andriy Marko

25. ledna 2018 18:21

Advanced Materials and Nanotechnology Seminar Series 2018: Dr Andriy…

WHEN: 30. 01. 2018 WHERE: CEITEC BUT, Purkynova 123, large meeting room SPEAKER: Dr Andriy Marko TALK: Advances in PELDOR…