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Advanced Nano and Microtechnologies Advanced Materials Structural Biology Gen. and Prot. of Plant Systems Molecular Medicine Brain and Mind Research Molecular Vet. Medicine

Multi-modal and Functional Neuroimaging - Ivan Rektor

Research Group Leader
Researcher ID
Phone: +420 54949 6057, +420 543 182 623
E-mail:
Office:

Research areas

  • Research of advanced recordings, data analysis and multimodal integration methods (MRI, HD EEG, fMRI/EEG) in brain mapping
  • Understanding the role and interactions of cortical and subcortical functions in processing higher level brain activities in health and disease
  • Development and implementation of advanced methods for CF MAFIL
  • Research on epilepsy, Parkinson’s disease, vascular parkinsonism, cognitive functions, writing, music, and stress resilience

Main objectives

  • Development of new molecular and functional imaging methods and their translation into clinical neuroscience.
  • Usage of the multimodal approach to the advanced study of cognitive and behavioural functions.

Content of research

Four basic approaches enabling study of the

a. subcortical structures and their interaction with the cortex

b. large scale brain networks in healthy and diseased brain predominantly cortical/ predominantly subcortical diseases (Epilepsy / Parkinson´s disease,  dystonia)

  • electrophysiological recording from deep structures (Subthalamic ncl.,  Anterior Nucleus of Thalamus, Pallidum )
  • High density electrophysiological recording from cortical structures
  • functional, structural and metabolic imaging with MRI techniques
  • EEG-fMRI: a combination of simultaneous fMRI recording and electrophysiological recording

Data analysis with advanced mathematical methods are performed in cooperation with ISI AS CR, CERIT MU

Projects

Music Lovers Club

The project consists of two parts. First is intracranial EEG study focused on the impact of music on epilepsy. Second part involves research of the brain connectivity related to music in professional and non-professionals. This part focuses on analysis of functional connectivity and extent of brain cognitivity involvment while listening to classical music by professional players versus passive listeners. The design of the study includes listening to an excerpt of classical music chosen by the subject and listening to subject’s beforehand unknown excerpt. We will test the hypothesis whether professional players connect cognitive component more then passive listeners while listening to classical music. We will particulary focus on networks analysis.

Supported by NPU II.

Modulation of functional connectivity of the large scale cortical networks by STN DBS

Deep brain stimulation (DBS) is an effective long-term treatment for motor symptoms in advanced Parkinson's disease (PD). The most frequently used target is the subthalamic nucleus (STN). For some patients, the beneficial motor effects may be accompanied by cognitive impairment and other neuropsychiatric disturbances. Thus, we use scalp high-density EEG under on and off conditions and also intracerebral recordings of the STN combined with scalp recording in the subgroup. Advanced analytical methods are used to clarify the STN DBS impact on motor and cognitive cortical networks and correlated with longitudinal clinical examination. The project is intended to identify changes in cortical functional connectivity produced by DBS-STN stimulation in order to optimalize the treatment, and to find a possible predictive marker of cognitive impairment linked with DBS.

Supported by AZV-16-33798A Modulation of functional connectivity of the large scale cortical networks by STN DBS

Data-driven filtering of fMRI data

This project focuses on comparison and evaluation of possible approaches for data-driven filtering of fMRI data. This kind of filtering uses signals from white matter and cerebrospinal fluid. The aim of project is to compare suitability of particular extraction options and also the exact regions from which the signals can be extracted. The criterion for comparison of particular approaches is the ammount of explained noise variability in data (desirable as high as possible) and supression of signals of neural origin (desirable as low as possible).

Supported by GA14-33143S.

Design and optimization of ultra-short echo-time sequence for reliable detection of myelin content in the human brain by magnetic resonance imaging

The aim of the project is to design and optimize an ultra-short echo-time pulse sequence for a direct measurement of the short-T2 signals arising from white matter of the brain. There are two main obstacles to a reliable detection of myelin sheaths: 1) their signal decays to zero in a few tens of microseconds; and 2) their signal is overwhelmed by the predominant long-T2 components from white matter of the brain. The unique feature of the pulse sequence design will be a calibration procedure correcting for eddy-current induced image distortions, based on the measurement of k-space trajectory during the gradient ramp-up. The complete removal of residual long-T2 components will be achieved by optimized dual echo acquisition and subtraction, which will selectively depict signal from the short-T2 components. Following the technical development, a pilot study including healthy and multiple sclerosis volunteers will be performed to demonstrate the capabilities of the newly developed methodology for the direct myelin measurement.

Supported by Czech Science Foundation grant no. GA15-12607S

Neurobiological and psychological markers of stress response and resilience in holocaust survivors and their offspring - a three generation study

The goal of the project "Neurobiological and psychological markers of stress response and resilience in holocaust survivors and their offspring - a three generation study" is to identify the neurobiological, psychological and genetic markers of stress response and resilience in shoa (holocaust) survivors and investigate transmission of trauma in two generations of their offspring as compared to age-, gender- and education- matched control subjects.

Supported by Czech Bioimaging and Foundation for holocaust victims.

Lesion detection in non-lesional epilepsies using multimodal imaging methods

The project is focused on identification of previously unidentified brain structural or functional lesions that are potential seizure onset zones. Advanced functional and structural imaging methods will be combined to detect lesions: high density EEG; simultaneous HD EEG-fMRI; arterial spin labeling; advanced high-resolution structural imaging; diffusion tract and kurtosis imaging. We presume that subtle lesion will be defined by advanced multimodal imaging. The goal is introduction of validated protocols in the routine clinical practice.

Supported by NPU II.

 

list / cards

Name and position

E-mail

Phone

Prof. MUDr. Ivan Rektor, CSc.
Research Group Leader
+420 54949 6057, +420 543 182 623
Martina Bočková, Ph.D.
Researcher
+420 543 182 683
Petr Bob, Ph.D.
Researcher
Marek Baláž, Ph.D.
Researcher
+420 543 182 645
Alena Damborská, Ph.D.
Researcher
+420 54949 7454, +420 532 232 050
Peter Latta
Researcher, MR physicist
+420 54949 5622
Michal Mikl, Ph.D.
Head of Core Facility
+420 54949 6099
Marek Bartoň
Specialist
+420 54949 5432
Radek Mareček
Deputy Laboratory Leader, Specialist
+420 54949 7775, +420 543 182 641
Lenka Zahradníková
Secretary
+420 543 182 658
Martin Lamoš
Specialist, assistant administrator electrophysiology
+420 54949 7801
Anna Wojna Pelczar, Ph.D.
odborná pracovnice ve výzkumu - postdoc
+420 54949 8215
Eva Štipčáková
Specialist, operator MR
+420 54949 7774
Pavel Říha
odborný pracovník - PhD student
+420 54949 5432
Martin Gajdoš
Specialist
+420 54949 4031
Eva Koriťáková
analytička
+420 775 892 513, +420 54949 3158
Patrícia Klobušiaková
MR Operator
+420 54949 8446
Jan Fousek
odborný pracovník
Monika Fňašková
odborná pracovnice - PhD student
+420 54949 7774
Eva Výtvarová
odborná pracovnice - PhD student
+420 54949 6374
Tereza Pařilová
+420 54949 7774
Alena Svátková
Medical Specialist
Lubomír Vojtíšek, Ph.D.
Specialist, Manager MR equipments
+420 54949 7779
Michael Teodor Grey
Branislav Veselý
PhD student
Barbora Sklenárová
Pavel Daniel
Specialist
+420 54949 8197, +420 543 182 641
Klára Štillová
PhD student
+420 543 182 645
Petr Krupa
Medical Specialist
Vlasta Dírerová
Petr Bednařík
Medical Specialist
+420 543 183 034
Sabina Goldemundová
Psychologist
+420 543 182 660
Barbora Deutschová
Ondřej Strýček
Vendula Hálková
Project Financial Manager
+420 54949 6098
Martin Kojan
Specialist, Manager EEG laboratory
+420 54949 8197
Tomáš Slavíček
Specialist
+420 54949 7800
Marta Zedníčková
Boguslaw Tomanek
Researcher
Zenon Starčuk
Deputy Laboratory Leader, MR physicist
Zdeněk Novák
Senior Researcher
Hana Pavlicová
Technician
Petr Mikulenka
PhD student

SELECTED PUBLICATIONS

2017

  • ANDERKOVA, L; BARTON, M; REKTOROVA, I, 2017:Striato-cortical Connections in Parkinson's and Alzheimer's Diseases: Relation to Cognition. MOVEMENT DISORDERS 32 (6), p. 917 - 921.
  • BEDNARIK, P; TKAC, I; GIOVE, F; EBERLY, L. E; DEELCHAND, D. K; BARRETO, F. R; MANGIA, S, 2017:Neurochemical responses to chromatic and achromatic stimuli in the human visual cortex. Journal of Cerebral Blood Flow & Metabolism
  • BRAZDIL, M; PAIL, M; HALAMEK, J; PLESINGER, F; CIMBALNIK, J; ROMAN, R; KLIMES, P; DANIEL, P; CHRASTINA, J; BRICHTOVA, E; REKTOR, I; WORRELL, GA; JURAK, P, 2017:INTERICTAL VERY FAST RIPPLES (500-1000 HZ) AND ULTRA FAST RIPPLES (1-2 KHZ): NOVEL BIOMARKERS OF THE EPILEPTOGENIC ZONE. EPILEPSIA 58 , p. S94 - S94.
  • BRAZDIL, M; PAIL, M; HALAMEK, J; PLESINGER, F; CIMBALNIK, J; ROMAN, R; KLIMES, P; DANIEL, P; CHRASTINA, J; BRICHTOVA, E; REKTOR, I; WORRELL, GA; JURAK, P, 2017:Very High-Frequency Oscillations: Novel Biomarkers of the Epileptogenic Zone. ANNALS OF NEUROLOGY 82 (2), p. 299 - 310.
  • DOLEZALOVA, I; SCHACHTER, S; CHRASTINA, J; HEMZA, J; HERMANOVA, M; REKTOR, I; PAZOURKOVA, M; BRAZDIL, M, 2017:Atypical handedness in mesial temporal lobe epilepsy. EPILEPSY & BEHAVIOR 72 , p. 78 - 81.
  • FILIP, P; GALLEA, C; LEHERICY, S; BERTASI, E; POPA, T; MARECEK, R; LUNGU, O; KASPAREK, T; VANICEK, J; BARES, M., 2017:Disruption in cerebellar and basal ganglia networks during a visuospatial task in cervical dystonia. Movement Disorders
  • KHAIRNAR, A; RUDA-KUCEROVA, J; SZABO, N; DRAZANOVA, E; ARAB, A; HUTTER-PAIER, B; NEDDENS, J; LATTA, P; STARCUK, Z; REKTOROVA, I, 2017:Early and progressive microstructural brain changes in mice overexpressing human alpha-Synuclein detected by diffusion kurtosis imaging. BRAIN BEHAVIOR AND IMMUNITY 61 , p. 197 - 208.
  • KLIMES, P; JURAK, P; HALAMEK, J; BOCKOVA, M; DAMBORSKA, A; DOLEZALOVA, I; STILLOVA, K; BALAZ, M; DANIEL, P; BRAZDIL, M; REKTOR, I, 2017:INTRATHALAMIC HIGH-FREQUENCY EEG CAN PREDICT DEEP BRAIN STIMULATION EFFICACY IN EPILEPSY. EPILEPSIA 58 , p. S187 - S187.
  • KUKLETA, M; DAMBORSKA, A; TURAK, B; LOUVEL, J, 2017:Evoked potentials in final epoch of self-initiated hand movement: A study in patients with depth electrodes. INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY 117 , p. 119 - 125.
  • VYTVAROVA, E; MARECEK, R; FOUSEK, J; STRYCEK, O; REKTOR, I, 2017:Large-scale cortico-subcortical functional networks in focal epilepsies: The role of the basal ganglia. 14 , p. 28 - 36.

2016

  • BOB, P; LAKER, M, 2016:Traumatic stress, neural self and the spiritual mind. CONSCIOUSNESS AND COGNITION 46 , p. 7 - 14.
  • CZEKOOVA, K; SHAW, DJ; URBANEK, T; CHLADEK, J; LAMOS, M; ROMAN, R; BRAZDIL, M, 2016:What's the meaning of this? A behavioral and neurophysiological investigation into the principles behind the classification of visual emotional stimuli. PSYCHOPHYSIOLOGY 53 (8), p. 1203 - 1216.
  • DAMBORSKA, A; ROMAN, R; BRAZDIL, M; REKTOR, I; KUKLETA, M, 2016:Post-movement processing in visual oddball task - Evidence from intracerebral recording. CLINICAL NEUROPHYSIOLOGY 127 (2), p. 1297 - 1306.
  • ELFMARKOVA, N; GAJDOS, M; MRACKOVA, M; MEKYSKA, J; MIKL, M; REKTOROVA, I, 2016:Impact of Parkinson's disease and levodopa on resting state functional connectivity related to speech prosody control. PARKINSONISM & RELATED DISORDERS 22 , p. S52 - S55.
  • GAJDOS, M; MIKL, M; MARECEK, R, 2016:Mask_explorer: A tool for exploring brain masks in fMRI group analysis. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 134 , p. 155 - 163.
  • KLEIN, P; TYRLIKOVA, I; BRAZDIL, M; REKTOR, I, 2016:Brivaracetam for the treatment of epilepsy. EXPERT OPINION ON PHARMACOTHERAPY 17 (2), p. 283 - 295.
  • KUKLETA, M; DAMBORSKA, A; ROMAN, R; REKTOR, I; BRAZDIL, M, 2016:The primary motor cortex is involved in the control of a non-motor cognitive action. CLINICAL NEUROPHYSIOLOGY 127 (2), p. 1547 - 1550.
  • LOSAK, J; HUTTLOVA, J; LIPOVA, P; MARECEK, R; BARES, M; FILIP, P; ZUBOR, J; USTOHAL, L; VANICEK, J; KASPAREK, T, 2016:Predictive Motor Timing and the Cerebellar Vermis in Schizophrenia: An fMRI Study. SCHIZOPHRENIA BULLETIN 42 (6), p. 1517 - 1527.
  • MARECEK, R; LAMOS, M; MIKL, M; BARTON, M; FAJKUS, J; REKTOR, I; BRAZDIL, M, 2016:What can be found in scalp EEG spectrum beyond common frequency bands. EEG-fMRI study. JOURNAL OF NEURAL ENGINEERING 13 (4)
  • REKTOR, I; DOLEZALOVA, I; CHRASTINA, J; JURAK, P; HALAMEK, J; BALAZ, M; BRAZDIL, M,, 2016:High-Frequency Oscillations in the Human Anterior Nucleus of the Thalamus. BRAIN STIMULATION 9 (4), p. 629 - 631.
  • REKTOROVA, I; MEKYSKA, J; JANOUSOVA, E; KOSTALOVA, M; ELIASOVA, I; MRACKOVA, M; BERANKOVA, D; NECASOVA, T; SMEKAL, Z; MARECEK, R, 2016:Speech prosody impairment predicts cognitive decline in Parkinson's disease. PARKINSONISM & RELATED DISORDERS 29 , p. 90 - 95.
  • RYZI, M; OSLEJSKOVA, H; REKTOR, I; NOVAK, Z; HEMZA, J; CHRASTINA, J; SVOBODA, M; HERMANOVA, M; BRAZDIL, M, 2016:Long-term approach to patients with postsurgical seizures. EPILEPSIA 57 (4), p. 597 - 604.
  • SHAW, DJ; MARECEK, R; GROSBRAS, MH; LEONARD, G; PIKE, GB; PAUS, T, 2016:Co-ordinated structural and functional covariance in the adolescent brain underlies face processing performance. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE 11 (4), p. 556 - 568.
  • SVATKOVA, A; NESTRASIL, I; RUDSER, K; FINE, JG; BLEDSOE, J; SEMRUD-CLIKEMAN, M, 2016:Unique White Matter Microstructural Patterns in ADHD Presentations-A Diffusion Tensor Imaging Study. HUMAN BRAIN MAPPING 37 (9), p. 3323 - 3336.
  • TERPSTRA, M; CHEONG, I; LYU, T; DEELCHAND, DK; EMIR, UE; BEDNARIK, P; EBERLY, LE; OZ, G, 2016:Test-Retest Reproducibility of Neurochemical Profiles with Short-Echo, Single-Voxel MR Spectroscopy at 3T and 7T. MAGNETIC RESONANCE IN MEDICINE 76 (4), p. 1083 - 1091.
  • VESELY, B; REKTOR, I, 2016:The contribution of white matter lesions (WML) to Parkinson's disease cognitive impairment symptoms: A critical review of the literature. PARKINSONISM & RELATED DISORDERS 22 , p. S166 - S170.

2015

  • BEDNARIK, P; MOHEET, A; DEELCHAND, DK; EMIR, UE; EBERLY, LE; BARES, M; SEAQUIST, ER; OZ, G, 2015:Feasibility and reproducibility of neurochemical profile quantification in the human hippocampus at 3T. NMR IN BIOMEDICINE 28 (6), p. 685 - 693.
  • BEDNARIK, P; TKAC, I; GIOVE, F; DINUZZO, M; DEELCHAND, DK; EMIR, UE; EBERLY, LE; MANGIA, S, 2015:Neurochemical and BOLD responses during neuronal activation measured in the human visual cortex at 7 Tesla. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35 (4), p. 601 - 610.
  • BOB, P; SELESOVA, P; RABOCH, J; KUKLA, L, 2015:Dissociative Symptoms and Mother's Marital Status in Young Adult Population. MEDICINE 94 (2)
  • BOCKOVA, M; CHLADEK, J; JURAK, P; HALAMEK, J; STILLOVA, K; BALAZ, M; CHRASTINA, J; REKTOR, I, 2015:Complex Motor-Cognitive Factors Processed in the Anterior Nucleus of the Thalamus: An Intracerebral Recording Study. BRAIN TOPOGRAPHY 28 (2), p. 269 - 278.
  • SHAW, D J; MARECEK, R; BRAZDIL, M., 2015:Structural co-variance mapping delineates medial and medio-lateral temporal networks in déjà vu. Brain Imaging and Behaviour 10 (4), p. 1068 - 1079.
  • STILLOVA, K; JURAK, P; CHLADEK, J; CHRASTINA, J; HALAMEK, J; BOCKOVA, M; GOLDEMUNDOVA, S; RIHA, I; REKTOR, I, 2015:The Role of Anterior Nuclei of the Thalamus: A Subcortical Gate in Memory Processing: An Intracerebral Recording Study. PLOS ONE 10 (11)
  • SVATKOVA, A; MANDL, RCW; SCHEEWE, TW; CAHN, W; KAHN, RS; POL, HEH, 2015:Physical Exercise Keeps the Brain Connected: Biking Increases White Matter Integrity in Patients With Schizophrenia and Healthy Controls. SCHIZOPHRENIA BULLETIN 41 (4), p. 869 - 878.
  • ZEMANKOVA, P; LUNGU, O; KASPAREK, T; HUTTLOVA, J; KERKOVSKY, M; BARES, M, 2015:ABNORMAL MOVEMENT SEQUENCING IN SCHIZOPHRENIA AND RELATED CORTICAL ACTIVATION PATTERNS. SCHIZOPHRENIA BULLETIN 41 , p. S244 - S244.

2014

  • BOB, P; ROMAN, R; SVETLAK, M; KUKLETA, M; CHLADEK, J; BRAZDIL, M, 2014:Preictal Dynamics of EEG Complexity in Intracranially Recorded Epileptic Seizure A Case Report. MEDICINE 93 (23)
  • DOLEZALOVA, I; BRAZDIL, M; HERMANOVA, M; JANOUSOVA, E; KUBA, R, 2014:Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis. EPILEPSY RESEARCH 108 (8), p. 1406 - 1416.
  • DOLEZALOVA, I; BRAZDIL, M; HERMANOVA, M; KOJAN, M; KUBA, R, 2014:CLINICAL CHARACTERISTICS OF PATIENTS WITH REFRACTORY MRI-NEGATIVE, PET-POSITIVE TEMPORAL LOBE EPILEPSY. EPILEPSIA 55 , p. 239 - 239.
  • ELISAK, M; MARTINKOVIC, L; AMLEROVA, J; MUSILOVA, K; KUBA, R; BRAZDIL, M; MARUSIC, P, 2014:CLINICAL AND HISTOPATHOLOGICAL CHARACTERISTICS OF TEMPORAL LOBE EPILEPSY PATIENTS MANIFESTING WITH HYPERMOTOR SEIZURES. EPILEPSIA 55 , p. 61 - 62.
  • KWAN, P; TRINKA, E; VAN PAESSCHEN, W; REKTOR, I; JOHNSON, ME; LU, S, 2014:Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: Results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial. EPILEPSIA 55 (1), p. 38 - 46.
  • NESTRASIL, I; BEDNARIK, P; YUND, B; DELANEY, K; KOVAC, V; AHMED, A; SHAPIRO, E, 2014:Brain Mill abnormalities in mucopolysaccharidosis type I: cross-sectional Study. MOLECULAR GENETICS AND METABOLISM 111 (2), p. S81 - S81.
  • PEC, O; BOB, P; RABOCH, J, 2014:Splitting in Schizophrenia and Borderline Personality Disorder. PLOS ONE 9 (3)

2013

  • BRAZDIL, M; JANECEK, J; KLIMES, P; MARECEK, R; ROMAN, R; JURAK, P; CHLADEK, J; DANIEL, P; REKTOR, I; HALAMEK, J; PLESINGER, F; JIRSA, V, 2013:On the Time Course of Synchronization Patterns of Neuronal Discharges in the Human Brain during Cognitive Tasks. PLOS ONE 8 (5)
  • BRAZDIL, M; ZEMAN, A, 2013:The boundaries of epilepsy: Where is the limit? A reply to Labate and Gambardella. CORTEX 49 (4), p. 1163 - 1164.
  • GESCHEIDT, T; MARECEK, R; MIKL, M; CZEKOOVA, K; URBANEK, T; VANICEK, J; SHAW, DJ; BARES, M, 2013:Functional anatomy of outcome evaluation during Iowa Gambling Task performance in patients with Parkinson's disease: an fMRI study. NEUROLOGICAL SCIENCES 34 (12), p. 2159 - 2166.
  • KASPAREK, T; PRIKRYL, R; REHULOVA, J; MARECEK, R; MIKL, M; PRIKRYLOVA, H; VANICEK, J; CESKOVA, E, 2013:Brain functional connectivity of male patients in remission after the first episode of schizophrenia. HUMAN BRAIN MAPPING 34 (3), p. 726 - 737.
  • ROMAN, R; BRAZDIL, M; CHLADEK, J; REKTOR, I; JURAK, P; SVETLAK, M; DAMBORSKA, A; SHAW, DJ; KUKLETA, M, 2013:Hippocampal Negative Event-Related Potential Recorded in Humans During a Simple Sensorimotor Task Occurs Independently of Motor Execution. HIPPOCAMPUS 23 (12), p. 1337 - 1344.
  • SHAW, DJ; CZEKOOVA, K; CHROMEC, J; MARECEK, R; BRAZDIL, M, 2013:Copying You Copying Me: Interpersonal Motor Co-Ordination Influences Automatic Imitation. PLOS ONE 8 (12), p. e84820 - .
  • ZELINKOVA, J; SHAW, DJ; MARECEK, R; MIKL, M; URBANEK, T; PETERKOVA, L; ZAMECNIK, P; BRAZDIL, M, 2013:Superior temporal sulcus and social cognition in dangerous drivers. NEUROIMAGE 83 , p. 1024 - 1030.

2012

  • BRAZDIL, M; MARECEK, R; URBANEK, T; KASPAREK, T; MIKL, M; REKTOR, I; ZEMAN, A, 2012:Unveiling the mystery of deja vu: The structural anatomy of deja vu. CORTEX 48 (9), p. 1240 - 1243.
  • BRAZDIL, M; MARECEK, R; URBANEK, T; KASPAREK, T; MIKL, M; REKTOR, I; ZEMAN, A, 2012:UNVEILING THE MYSTERY OF DEJA VU. EPILEPSIA 53 , p. 57 - 57.
  • GESCHEIDT, T; CZEKOOVA, K; URBANEK, T; MARECEK, R; MIKL, M; KUBIKOVA, R; TELECKA, S; ANDRLOVA, H; HUSAROVA, I; BARES, M, 2012:Iowa Gambling Task in patients with early-onset Parkinson's disease: strategy analysis. NEUROLOGICAL SCIENCES 33 (6), p. 1329 - 1335.
  • OBHLIDALOVA, I; KERKOVSKY, M; STOURAT, P; BEDNARIK, P; VICKOVA, E, 2012:Imaging Techniques to Evaluate Morphological Correlates of Cognitive Dysfunction in Multiple Sclerosis Patients. CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE 75 (2), p. 170 - 178.
  • REKTOR, I; GOLDEMUND, D; BEDNARIK, P; SHEARDOVA, K; MICHALKOVA, Z; TELECKA, S; DUFEK, M; REKTOROVA, I, 2012:Impairment of Brain Vessels May Contribute to Mortality in Patients With Parkinson's Disease. MOVEMENT DISORDERS 27 (9), p. 1168 - 1172.
  • REKTOR, I; KUBA, R; BRAZDIL, M; CHRASTINA, J, 2012:Do the basal ganglia inhibit seizure activity in temporal lobe epilepsy?. EPILEPSY & BEHAVIOR 25 (1), p. 56 - 59.

2011

  • BOB, P; JASOVA, D; BIZIK, G; RABOCH, J, 2011:Epileptiform Activity in Alcohol Dependent Patients and Possibilities of Its Indirect Measurement. PLOS ONE 6 (4)
  • MUSILOVA, K; KUBA, R; BRAZDIL, M; TYRLIKOVA, I; REKTOR, I, 2011:PERIICTAL BED LEAVING IN TEMPORAL LOBE EPILEPSY: INCIDENCE AND LATERALIZING VALUE. EPILEPSIA 52 , p. 143 - 144.
  • REKTOR, I; TOMCIK, J; MIKL, M; MARECEK, R; BRAZDIL, M; REKTOROVA, I, 2011:ASSOCIATION BETWEEN BASAL GANGLIA AND LARGE SCALE BRAIN NETWORKS IN EPILEPSY. EPILEPSIA 52 , p. 175 - 176.

GRANTY

  • Design and optimization of ultra-short echo-time sequence for reliable detection of myelin content in the human brain by magnetic resonance imaging (GA15-12607S), Czech Science Foundation - Standard Grants, 2015 - 2017
  • Effect of intensive dance-exercise intervention on cognition and brain plasticity in healthy seniors and patients with mild cognitive impairment (15-33854A), Ministry of Health of the CR, 2015 - 2018
  • Modulation of functional connectivity in cortical networks with STN DBS (16-33798A), Ministry of Health of the CR, 2016 - 2019
  • Lesion detection in non-lesional epilepsies using multimodal imaging methods (15-33854A), Ministry of Health of the CR, 2017 - 2020
  • Czech-BioImaging – National research infrastructure for biological and medical imaging (LM2015062), Ministry of Education, Youth and Sports, 2016 - 2019
  • COBEN: Novel Network-Based Approaches for Studying Cognitive Dysfunction in Behavioral Neurology, , 2017 - 2020

PLANNED RESEARCH INFRASTRUCTURE

Core Facility

The research group will be one of the principal users of the equipment available within CEITEC Molecular and Functional Imaging Core Facility.

Technology Units

  • Computational neuroscience
  • Laboratory for cognitive and behavioral sciences
  • Pain research laboratory

CURRENT RESEARCH INFRASTRUCTURE

MR Siemens Magnetom Symphony 1.5T, MR compatible EEG (BrainAmp) 32 channels, Video EEG system (Alien) 128 channels, EEG system (BrainScope) 96 channels.

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