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1st Workshop on TP53 Analysis in CLL, 1st to 3rd October 2015

tp53-obr 1st Workshop on TP53 Analysis in CLL, 1st to 3rd October 2015

ERIC is very pleased to announce the launch of a European TP53 Network. The aim of the Network is to improve the performance of TP53 mutational analysis in diagnostic labs and to increase the assessment in the patients needing treatment, aiming at a better management of this high risk subset of CLL.
Initially, 8 regions in Europe will be involved, including: Czech Republic, France, Germany, Greece, Italy, Spain, Nordic countries and the UK, but in 2016 the Network will progressively be expanded to all other countries.
The TP53 Network will provide technical support,diagnostic help and educational activities to the diagnostic labs and practicing hematologists who have such requirements. Please refer to the http://www.ericll.org/pages/tp53network website for additional details and future updates.

As part of the educational activities of the TP53 Network, the 1ST ERIC Workshop On TP53 Analysis In Chronic Lymphocytic Leukemia will take place in Brno, Czech Republic on 1-3 October 2015. The meeting will focus on Technical approaches and data interpretation, troubleshooting, predictive and therapeutic implications.

INFORMATION:

Registration deadline: September 13, 2015

Accommodation for speakers is arranged by CEITEC -  FREE
Accommodation for participants is arranged by CEITEC - payment on the spot

Warning: Please do not respond to other agencies offering accommodation.

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PROGRAMME

October 1st

14:00 - 19:00 Registration  Univ. Campus - A11 
15:00 Bus from the hotel Holiday inn to the Univ. Campus  
16:00 - 16:15

Welcome speech - Paolo Ghia (IT), ERIC President, Šárka Pospíšilová (CZ), Head of Centre for Molecular Medicine, CEITEC, Masaryk University

Univ. Campus - A11 - lecture hall 114
16:15 - 17:15

Keynote lecture: Patricia Muller (GB)- 

Chair: Šárka Pospíšilová 

Univ. Campus - A11 - lecture hall 114
  p53 in health and disease  
17:15 - 17:40 Coffee break  
 

Session I: CLL genomics and the impact of p53 aberrations

Chair: Emili Montserrat

17:40 - 18:20 Lecture 1: Davide Rossi (IT) - The genomic landscape of CLL  Univ. Campus A11 - lecture hall 114
18:20 - 19:00 Lecture 2: Michael Doubek (CZ) - TP53 abnormalities in CLL:  therapeutic implications Univ. Campus A11 - lecture hall 114
19:05 Bus from the Univ. Campus to the hotel Holiday inn 
19:15 

Speakers´ dinner at city centre 

Restaurant Pavillon

19:30 Participants´ dinner  Hotel Holiday Inn

October 2nd

8:10 Bus from the hotel Holiday inn to the Univ. Campus
 

Session II: TP53 mutational analysis - databases, approaches and reporting

Chair: Andrew Pettit, Florence Cymbalista

08:30 - 09:00          Lecture 3: Thierry Soussi (SWE) - TP53 mutational database and nomenclature Univ. Campus - A11 - lecture hall 114
09:00 - 10:00 Methodological approaches 1: Eugen Tausch (DE), Jitka Malcikova (CZ), Fanny Baran - Marszak (FR) - TP53 mutational analysis - methods and approaches, including NGS Univ. Campus A11 - lecture hall 114
10:00 - 10:30 Methodological approaches 2: Richard Rosenquist (SWE) - Experiences with CLL prognostic gene panel (ERIC project) Univ. Campus A11 - lecture hall 114
10:30 - 11:00 Coffee break   
 

Session II: TP53 mutational analysis - databases, approaches and reporting

Chair: Carol Moreno 

 
11:00 - 11:30 Methodological approaches 3: Arnon Kater (NL), Marek Mráz (CZ) - p53 function tests in relation to TP53 gene aberrations Univ. Campus A11 - lecture hall 114
11:30 - 12:00 Methodological approaches 4: Richard Rosenquist (SWE) - Data interpretation and reporting - How to report results to the clinicians Univ. Campus A11 - lecture hall 114
12:00 - 12:30 Accreditation Report: Eugen Tausch (DE), Stephan Stilgenbauer (DE) - Experiences from the ERIC TP53 accreditation 2014 Univ. Campus A11 - lecture hall 114
12:30 - 13:00 Technical considerations: Alexander Jethwa (DE) Univ. Campus A11 - lecture hall 114
13:00 - 13:30 Discussion on Troubleshooting and technical recommendations - all speakers of Session II Univ. Campus A11 - lecture hall 114
13:30 - 14:30 Lunch   

 

 

Session III: Practical workshop

 

14:30 - 16:30

Practical workshop

participant groups in different rooms

CEITEC - A35 building 
16:30 - 17:00 Coffee break  
17:00 - 18:00 Laboratory tour: Šárka Pospíšilová (CZ), Boris Tichý (CZ) CEITEC sequencing facility
 

Session IV: Prognostication in CLL: happy with aberrations p53 only?

Chair: Kostas Stamatopoulos

18:00 - 18:30 Lecture 4: Gianluca Gaidano Prognostication in CLL: present and future Univ. Campus - A11 - lecture hall 114

 

18:30 - 18:50

 

Panel discussion

Univ. Campus - A11 - lecture hall 114

18:50 - 19:00

Meeting close: Šárka Pospíšilová (CZ), Paolo Ghia  (IT) - Conclusions on TP53 Network

Univ. Campus A11 - lecture hall 114
19:30 Bus from Campus MU Main Entrance to the Observatory
20:00 - 22:30 Social event and dinner Observatory
 

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ghia

Paolo Ghia
 Università Vita-Salute San Raffaele

šárka

Šárka Pospíšilová

CEITEC MU, Brno

muller2

Patricia Muller

University of Leicester

rossi

Davide Rossi

University of Piemonte Orientale “Amedeo Avogadro”

stilgenbauer

Stephan Stilgenbauer

Ulm University

soussi

Thierry Soussi

Karolinska Institutes

tausch

Eugen Tausch

Ulm University

 

 

 

 

 

 

Jitka Malčíková

CEITEC MU, Brno

 

 

 

 

 

Fanny Baran - Marszak

Hôpitaux Universitaires Paris-Seine-Saint-Denis-APHP-Hôpitaux Universitaires Avicenne 

rosenquist

Richard Rosenquist

Uppsala universitet

kater

Arnon Kater

University of Amsterdam

marek mraz

Marek Mráz
CEITEC MU, Brno

zenz

Thorsten Zenz

Heidelberg University Hospital 

tichý

Boris Tichý

CEITEC MU, Brno

gaidano

Gianluca Gaidano

University of Piemonte Orientale “Amedeo Avogadro”

 

 

 

 

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TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop TP53 Workshop

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