Nonhydrolytic sol-gel syntheses of nanoporous metal oxides, phosphates, and silicates. Synthesis and assembly of molecular building blocks into new materials. Sonochemical methods of nanoparticle synthesis, synthesis of alloy nanoparticles, synthesis of inorganic-organic complex materials, coordination and modified polymers and supramolecular entities. Surface mounted functional molecules. All the methods developed will be utilized directly for the fabrication of nanostructures, advanced materials and devices.
Characterization and optimization of the functional properties of nanostructures for catalysis, nanoelectronics, nanophotonics and (bio)sensing; and their correlation with compositional, morphological, and structural parameters. Theoretical ab initio electronic structure calculations of structural, magnetic, and thermodynamic properties of materials. Novel and unique properties of nanostructures not observable in conventional materials and microstructures open ways to qualitatively new applications.
Development of methods and techniques into higher functional integrated systems, optimized nanocatalysts, soldering formulation based on nanoalloy particles, nano- and micro-analytical systems and sensors and advanced materials for them. Nanostructures implemented into these systems will enhance the performance and efficiency of devices and systems and widen the areas for their applications e.g. in catalysis, separation, soldering, mapping and imaging, biosensing, biorecognition.
Development of the techniques and methodologies for analysis of nanomaterials/nanostructures and for diagnostics of their properties – new techniques of elemental mapping, microanalysis, MS surface imaging, medical diagnostics, and biosensing. This will be used to meet the other objectives of the Advanced Nanotechnologies and Microtechnologies Research Programme and characterization of nano- and micro-structures in general.
The preparation of nanomaterials by means of ultrasound and thermolytic methods – synthesis of nanoscopic metals, alloys, and metal oxides from newly designed precursors. The study of the mechanisms of sonochemical and thermolytic transformations of molecular precursors to solid-state products and ways to control these reactions. Emphasis on gaining control over the chemical constitution, phase composition, and morphology of the synthesized nanoparticles.
HRTEM image of the nanoalloy particles Cu20Ni
Synthesis of inorganic-organic materials – complexes, coordination polymers, modified polymers and supramolecular systems.
The development of methods for the preparation of molecular building blocks for the construction of new functional materials using the bottom-up approach. The complete characterization of the structure of new molecular species suitable for forming higher molecular, supramolecular, polymeric, and nanostructured systems. Studies of molecular features providing functionalities for binding or cross-linking leading to porous materials, metallo-organic, coordination and organic polymers. Studies of chemical properties including intermolecular interactions and self-organization properties. Tuning physico-chemical properties and experimental conditions influencing precursor reactivity for kinetic control of reactions. The expected applications are mainly aimed at catalysis, opto-electronics, nano-solders, gas storage, sensors in bio-analytical chemistry, self-assembled monolayers, the development of molecular machines, etc.
The development of methods and methodologies for the analysis of nanomaterials, nanostructures, for measuring their properties and the development of new analytical/diagnostic equipment and components. To surpass the limits of individual methods and the ambiguities of their results on the local characterization of individual nanoobjects the combinations of more analytical techniques and procedures will be developed.
Methods, such as desorption mass spectrometry with nanoparticle matrix (MALDI/SALDI TOF MS), high–throughput off-line analysis of microcolumn fractions (CE/HPLC – MALDI TOF MS), simultaneous detection: MALDI/ICP MS, fluorescence, capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) will be developed.
Mass spectrometry imaging and laser ablation-ICP-MS and Laser Induced Breakdown Spectroscopy (LIBS) elemental mapping will be applied to many diverse types of samples, such as corroded layers for structural materials of molten salt reactors (MSR), geological and archaeological samples, biominerals and biological samples.
Nonhydrolytic sol-gel syntheses of nanoporous metal oxides, phosphates, and silicates. Synthesis and assembly of molecular building blocks into new materials. Sonochemical methods of nanoparticle synthesis, synthesis of alloy nanoparticles, synthesis of inorganic-organic complex materials, coordination and modified polymers and supramolecular entities. Surface mounted functional molecules. All the methods developed will be utilized directly for the fabrication of nanostructures, advanced materials and devices.
Characterization and optimization of the functional properties of nanostructures for catalysis, nanoelectronics, nanophotonics and (bio)sensing; and their correlation with compositional, morphological, and structural parameters. Theoretical ab initio electronic structure calculations of structural, magnetic, and thermodynamic properties of materials. Novel and unique properties of nanostructures not observable in conventional materials and microstructures open ways to qualitatively new applications.
Development of methods and techniques into higher functional integrated systems, optimized nanocatalysts, soldering formulation based on nanoalloy particles, nano- and micro-analytical systems and sensors and advanced materials for them. Nanostructures implemented into these systems will enhance the performance and efficiency of devices and systems and widen the areas for their applications e.g. in catalysis, separation, soldering, mapping and imaging, biosensing, biorecognition.
Development of the techniques and methodologies for analysis of nanomaterials/nanostructures and for diagnostics of their properties – new techniques of elemental mapping, microanalysis, MS surface imaging, medical diagnostics, and biosensing. This will be used to meet the other objectives of the Advanced Nanotechnologies and Microtechnologies Research Programme and characterization of nano- and micro-structures in general.
The preparation of nanomaterials by means of ultrasound and thermolytic methods – synthesis of nanoscopic metals, alloys, and metal oxides from newly designed precursors. The study of the mechanisms of sonochemical and thermolytic transformations of molecular precursors to solid-state products and ways to control these reactions. Emphasis on gaining control over the chemical constitution, phase composition, and morphology of the synthesized nanoparticles.
HRTEM image of the nanoalloy particles Cu20Ni
Synthesis of inorganic-organic materials – complexes, coordination polymers, modified polymers and supramolecular systems.
The development of methods for the preparation of molecular building blocks for the construction of new functional materials using the bottom-up approach. The complete characterization of the structure of new molecular species suitable for forming higher molecular, supramolecular, polymeric, and nanostructured systems. Studies of molecular features providing functionalities for binding or cross-linking leading to porous materials, metallo-organic, coordination and organic polymers. Studies of chemical properties including intermolecular interactions and self-organization properties. Tuning physico-chemical properties and experimental conditions influencing precursor reactivity for kinetic control of reactions. The expected applications are mainly aimed at catalysis, opto-electronics, nano-solders, gas storage, sensors in bio-analytical chemistry, self-assembled monolayers, the development of molecular machines, etc.
The development of methods and methodologies for the analysis of nanomaterials, nanostructures, for measuring their properties and the development of new analytical/diagnostic equipment and components. To surpass the limits of individual methods and the ambiguities of their results on the local characterization of individual nanoobjects the combinations of more analytical techniques and procedures will be developed.
Methods, such as desorption mass spectrometry with nanoparticle matrix (MALDI/SALDI TOF MS), high–throughput off-line analysis of microcolumn fractions (CE/HPLC – MALDI TOF MS), simultaneous detection: MALDI/ICP MS, fluorescence, capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) will be developed.
Mass spectrometry imaging and laser ablation-ICP-MS and Laser Induced Breakdown Spectroscopy (LIBS) elemental mapping will be applied to many diverse types of samples, such as corroded layers for structural materials of molten salt reactors (MSR), geological and archaeological samples, biominerals and biological samples.
list / cards
Name and position |
Phone |
|
---|---|---|
Prof. Jiří Pinkas, Ph.D. Research Group Leader |
+420 54949 6493 | |
Prof. Mojmír Šob Senior Researcher |
+420 54949 7450 | |
Pavel Brož, Ph.D. Senior Researcher |
+420 54949 3299, +420 54949 5768 | |
Prof. Viktor Kanický Senior Researcher |
+420 54949 4774 | |
Přemysl Lubal, Ph.D. Senior Researcher |
+420 54949 5917, +420 54949 5637, +420 54949 6785, +420 54949 5926 | |
Ctibor Mazal Senior Researcher |
+420 54949 1429, +420 54949 5801 | |
Marek Nečas, Ph.D. Senior Researcher |
+420 54949 6060 | |
Jiří Sopoušek Senior Researcher |
+420 54949 7138, +420 54949 5768 | |
Prof. Jan Vřešťál Senior Researcher |
+420 54949 8134 | |
Markéta Holá, Ph.D. Researcher |
+420 54949 4285, +420 54949 5928 | |
Jana Pavlů, Ph.D. Researcher |
+420 54949 3742 | |
Petr Táborský, Ph.D. Researcher |
+420 54949 7618, +420 54949 5935 | |
Tomáš Vaculovič, Ph.D. Researcher |
+420 54949 5312, +420 54949 5928 | |
Michaela Vašinová Galiová, Ph.D. Researcher |
+420 54949 3666 | |
Monika Všianská, Ph.D. Specialist |
+420 54949 5659 | |
Lucie Šimoníková Laboratory technician |
+420 54949 3136, +420 54949 2534 | |
Vladimíra Veselská Accountant |
+420 54949 1472, +420 54949 8019 | |
Helena Zavadilová Laboratory technician |
+420 54949 3441, +420 54949 5868, +420 54949 8233 | |
Aleš Hrdlička, Ph.D. Junior researcher |
+420 54949 3518 | |
Karel Novotný, Ph.D. Senior Researcher |
+420 54949 6231 | |
Prof. Jan Preisler, Ph.D. Senior Researcher |
+420 54949 6629 | |
Michal Rájecký, Ph.D. PhD student |
+420 54949 6649, +420 54949 7564 | |
Iva Benešová, Ph.D. PhD student |
||
Martin Sojka PhD student |
||
Aleš Stýskalík, Ph.D. PhD student |
||
Jiří Nováček, Ph.D. Head of Core Facility |
+420 54949 3893 | |
Jiří Nečas sklofoukač |
||
Vít Vykoukal PhD student |
||
Iaroslav Doroshenko odborný pracovník - PhD student |
||
Tomáš Komárek |
||
Jakub Bělehrad |
||
Aneta Holemářová |
||
Petr Chrást |
||
Iva Kollhammerová PhD student |
||
Vojtěch Kopecký |
||
Nikola Koutná |
||
Tereza Kuběnová |
||
Petra Kučerová PhD student |
||
Petr Macháč |
||
Martina Mazalová |
||
Petr Pavlů |
||
Bhimrao Vaijnath Phulwale PhD student |
||
Ján Podhorský PhD student |
||
František Zelenák |
||
Daniela Petříková |
||
Adam Pruška |
+420 54949 2535 | |
Václav Vávra Researcher |
||
David Škoda PhD student |
Material synthesis (glove box, ultrasonic processor, tube furnaces, high-pressure autoclaves, microwave reactors); diffraction techniques (single-crystal X-ray diffractometer at variable temperatures); elemental analyses (ICP/OES spectrometer, ICP/MS spectrometer); mass spectrometry (TOF and quadrupole mass spectrometers); vibrational spectroscopy (FT-IR spectrometer, FT-Raman spectrometer); laser ablation systems; molecular spectroscopy (UV/Vis spectrometers, spectrofluorimeter); nuclear magnetic resonance (solution and solid-state NMR spectroscopy), computer cluster consisting of ten linked computers, WIEN2K, VASP and ABINIT codes; thermal analysis (DSC/DTA), high-temperature Knudsen effusion mass spectrometry (KEMS).
Supervisor: prof. Mgr. Jan Preisler, Ph.D.
Consultants: Mgr. Antonín Bednařík, Ph.D.
Mass spectrometry imaging (MSI) exploits the ability of mass spectrometry to identify molecules according to their specific mass and image their distribution across the sample. The method allows direct visualization of endogenous compounds (lipids, proteins, saccharides) as well as exogenous drugs and their metabolites. The aim of the research will be development of a suitable matrix-assisted laser desorption/ionization (MALDI) MSI method for the study of distribution and the effect of chosen drug selected tissues and cell lines. Special attention will be devoted to sample preparation and matrix deposition (spray, sublimation, piezoelectric dispenser). The samples will be supplied by cooperating institutions (e.g. the Department of Experimental Biology, Experimental and Applied Neuropsychopharmacology, Centre for Neuroscience, the Department of Pharmacology, the Regional Centre for Applied Molecular Oncology). The analyzed compounds include endogenous compounds (lipids, glycans) as well as selected drugs.
Keywords: mass spectrometry imaging, MSI, matrix-assisted laser desorption/ionization,MALDI, analysis development
29. ledna 2018 9:46
LECTURE: Dr. Ondrej Hovorka: Models of magnetic nanoparticles for biomedical applications
25. ledna 2018 18:21
WHEN: 30. 01. 2018 WHERE: CEITEC BUT, Purkynova 123, large meeting room SPEAKER: Dr Andriy Marko TALK: Advances in PELDOR…